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Extended Data Figure 5 A near-atomic resolution model of the hGLP-1rGLP-1RG s complex

For GLP-1 users specifically, I prioritize movements that protect the muscle groups most vulnerable to atrophy during rapid weight loss: Lower body: Squats ( meaning any form of knee bend), deadlifts, lunges (glutes, quads, and hamstrings are the largest muscle groups and the biggest contributors to metabolic rate) Upper back and lats: Rows, pulldowns (postural muscles that deteriorate quickly without stimulus) Chest and shoulders: Presses, overhead work, flyes (functional pushing strength) Core: Planks, Pallof presses, loaded carries (spinal stability, injury prevention) Safety Note: If nausea is severe during early titration, reduce training volume (fewer sets per exercise) rather than eliminating sessions

Aim for 8-10 glasses per day

Based on the available clinical evidence, Mounjaro has demonstrated greater weight loss results compared to Ozempic